Immunobiology of Dendritic Cells and Immunotherapy

Selected publications

• Rotta G, Matteoli G, Mazzini E, Nuciforo P, Colombo MP, Rescigno M.
  Contrasting roles of SPARC-related granuloma in bacterial containment and in the induction of anti-Salmonella typhimurium immunity.
  J Exp Med. 2008 Mar 17;205(3):657-67. Epub 2008 Mar 3.
• Salucci V, Rimoldi M, Penati C, Sampietro GM, van Duist MM, Matteoli G, Saibeni S, Vecchi M, Ardizzone S, Porro GB, Rescigno M.
  Monocyte-derived dendritic cells from Crohn patients show differential NOD2/CARD15-dependent immune responses to bacteria.
  Inflamm Bowel Dis. 2008 Jan 31; [Epub ahead of print]
• Avogadri, F., Mittal, D. Saccheri, F Sarrafiore M., Ciocca M., Larghi P., Orecchia R, and Rescigno M.
  Intratumoral Salmonella typhimurium induces systemic antitumor immune response that is directed by low dose radiation to treat distal disease.
  Eur. J. Immunol. Accepted
• Martinoli C, Chiavelli A, and Rescigno M.
  Entry route of Salmonella typhimurium directs the type of induced immune response.
  Immunity, 2007 Dec;27(6):975-84.
• Iliev I.D., Matteoli G. and Rescigno M.
  The yin and yang of intestinal epithelial cells in controlling dendritic cell function.
  J. Exp. Med. 2007 Oct 1;204(10):2253-7.
• Rescigno M, Avogadri F, Curigliano G.
  Challenges and prospects of immunotherapy as cancer treatment. Biochim Biophys Acta.
  2007 Sep;1776(1):108-23.
• Rescigno M, Nieuwenhuis EE.
  The role of altered microbial signaling via mutant NODs in intestinal inflammation
  (2007) Curr Opin Gastroenterol. 23(1):21-6.
• Chieppa M, Rescigno M, Huang AY, Germain RN.
  Dynamic imaging of dendritic cell extension into the small bowel lumen in response to epithelial cell TLR engagement
  (2006). J Exp Med. 203(13):2841-52.]
• Rescigno M.
  CCR6(+) dendritic cells: the gut tactical-response unit.
  Immunity. 2006 May;24(5):508-10.
• Rimoldi, M., Chieppa, M., Salucci, V., Sonzogni, A., Nespoli, A., Viale, G., Allavena, P., Rescigno, M.
  Intestinal immune homeostasis is regulated by the cross-talk between epithelial cells and dendritic cells.
  (2005) Nat Immunol. 6:507-14.
• Rescigno M, Chieppa M.
  Gut-level decisions in peace and war.
  (2005) Nat Med. 11:254-5.
• Rimoldi, M., Chieppa, M., Vulcano, M., Allavena, P., Rescigno, M.
  Dendritic cells activated by bacteria or by bacteria-stimulated epithelial cells are functionally different.
  (2005) Blood. 106(8):2818-26.
• Avogadri F, Martinoli C, Petrovska L, Chiodoni C, Transidico P, Colombo MP, Dougan G, Rescigno M
  Cancer immunotherapy based on killing of Salmonella-infected tumour cells
  (2005) Cancer Res. 65:3920-7
• B. Kelsall and Rescigno M.
  Mucosal Dendritic Cells in Immunity and Inflammation
  (2004) Nat Immunol. 5:1091-1095
• Rotta G., Edwards EW, Sangaletti S., Bennett C., Ronzoni S., Colombo M.P., Steinman RM, Randolph G.J., and Rescigno M.
  Lipopolysaccharide or whole bacteria block the conversion of inflammatory monocytes into dendritic cells in vivo.
  (2003) J Exp Med. 198:1253-63.
• Rescigno M.
  Dendritic cells and the complexity of microbial infection.
  (2002) Trends in Microbiol. 10:425-431
• Rescigno M. and P. Borrow.
  The host-pathogen interaction: new themes from dendritic cell biology
  (2001). Cell, 106:267-70.
• Rescigno M., Urbano M., Valzasina B, Francolini M., Bonasio R., Kraehenbuhl JP, Granucci F, Ricciardi-Castagnoli P.
  Dendritic cells express occludin, establish junctions with gut epithelial cells and sample bacteria preserving epithelial barrier integrity.
  (2001). Nat Immunol. 2:361-367