Genetic of cancer and tumor angiogenesis in zebrafish

Selected publications

• Mione MC, Trede NS.
  The zebrafish as a model for cancer.
  Dis Model Mech. 2010 Mar 30. [Epub ahead of print]
• Mione M, Meijer AH, Snaar-Jagalska BE, Spaink HP, Trede NS
  Disease modeling in zebrafish: cancer and immune responses-a report on a workshop held in Spoleto, Italy, July 20-22, 2009.
  Zebrafish. 2009 Dec;6(4):445-51.
• Anelli V, Santoriello C, Distel M, Köster RW, Ciccarelli FD, Mione M.
  Global repression of cancer gene expression in a zebrafish model of melanoma is linked to epigenetic regulation.
  Zebrafish. 2009 Dec;6(4):417-24.
• Montero-Balaguer M, Swirsding K, Orsenigo F, Cotelli F, Mione M, Dejana E.
  Stable vascular connections and remodeling require full expression of VE-cadherin in zebrafish embryos.
  PLoS One. 2009 Jun 3;4(6):e5772.
• Bonauer A, Carmona G, Iwasaki M, Mione M, Koyanagi M, Fischer A, Burchfield J, Fox H, Doebele C, Ohtani K, Chavakis E, Potente M, Tjwa M, Urbich C, Zeiher AM, Dimmeler S.
  MicroRNA-92a controls angiogenesis and functional recovery of ischemic tissues in mice.
  Science. 2009 Jun 26;324(5935):1710-3.
• Deflorian G, Cinquanta M, Beretta C, Venuto A, Santoriello C, Baldessari D, Pezzimenti F, Aliprandi M, Mione M, de Marco A.
  Monoclonal antibodies isolated by large-scale screening are suitable for labeling adult zebrafish (Danio rerio) tissues and cell structures.
  J Immunol Methods. 2009 Jul 31;346(1-2):9-17.
• Meani N, Pezzimenti F, Deflorian G, Mione M, Alcalay M.
  The tumor suppressor PRDM5 regulates Wnt signaling at early stages of zebrafish development.
  PLoS ONE. 2009;4(1):e4273.
• Stone OA, Richer C, Emanueli C, van Weel V, Quax PH, Katare R, Kraenkel N, Campagnolo P, Barcelos LS, Siragusa M, Sala-Newby GB, Baldessari D, Mione M, Vincent MP, Benest AV, Al Haj Zen A, Gonzalez J, Bates DO, Alhenc-Gelas F, Madeddu P.
  Critical role of tissue kallikrein in vessel formation and maturation: implications for therapeutic revascularization.
  Arterioscler Thromb Vasc Biol. 2009 ;29(5):657-64.
• Santoriello C, Deflorian G, Pezzimenti F, Kawakami K, Lanfrancone L, d'Adda di Fagagna F, Mione M.
  Expression of H-RASV12 in a zebrafish model of Costello syndrome causes cellular senescence in adult proliferating cells.
  Dis Model Mech. 2009 2(1-2):56-67.
• Palamidessi A, Frittoli E, Garré M, Faretta M, Mione M, Testa I, Diaspro A, Lanzetti L, Scita G, Di Fiore PP.
  Endocytic trafficking of Rac is required for the spatial restriction of signaling in cell migration.
  Cell. 2008 11;134(1):135-47.
• Cheng KC; Members of the Zebrafish Community.
  Views on four key questions about zebrafish research.
  Zebrafish. 2008 Spring;5(1):9-24.
• Baldessari D, Mione M
  How to create the vascular tree? (Latest) help from the zebrafish
  Pharmacology & Therapeutics, 2008, Review, in press
• Pocock* R, Mione* M, Hussain S, Maxwell S, Pontecorvi M, Aslam S, Gerrelli D, Sowden JC, Woollard A.
  Neuronal function of Tbx20 conserved from nematodes to vertebrates
  Dev Biol, 2008 Article in Press
• Mione M, Baldessari D, Deflorian G, Nappo G, Santoriello C.
  How neuronal migration contributes to the morphogenesis of the CNS: insights from the zebrafish.
  Dev Neurosci. 2008 30:65-81.
• Potente M, Ghaeni L, Baldessari D, Mostoslavsky R, Rossig L, Dequiedt F, Haendeler J, Mione M, Dejana E, Alt FW, Zeiher AM, Dimmeler S.
  SIRT1 controls endothelial angiogenic functions during vascular growth.
  Genes Dev. 2007 21:2644-58.
• Costagli A, Felice B, Guffanti A, Wilson SW, Mione M.
  Identification of alternatively spliced dab1 isoforms in zebrafish.
  Dev Genes Evol. 2006 216:291-9.
• Mione M, Lele Z, Kwong CT, Concha ML, Clarke JD.
  Expression of pcp4a in subpopulations of CNS neurons in zebrafish.
  J Comp Neurol. 2006 495:769-87.
• Foucher I, Mione M, Simeone A, Acampora D, Bally-Cuif L, Houart C.
  Differentiation of cerebellar cell identities in absence of Fgf signalling in zebrafish Otx morphants.
  Development. 2006 133:1891-900.
• Jeong J, Einhorn Z, Mercurio S, Lee S, Lau B, Mione M, Wilson S, Guo S.
  Neurogenin1 is a determinant of zebrafish basal forebrain dopaminergic neurons and is regulated by the conserved zinc finger protein Tof/Fezl.
  Proc Natl Acad Sci U S A. 2006 103:5143-8.
• Aligianis I, Morgan N, Mione M, Johnson CA, Rosser E, Hennekam R, Adams G, Trembath R, Pilz D, Stoodley N, Moore AT, Wilson S, Maher E    
  Mutation in Rab3 GTPase-activating protein (RAB3GAP) noncatalytic subunit in a kindred with Martsolf syndrome.
  Am J Hum Genet. 2006 78:702-7.
• Colombo A, Reig G, Mione M, Concha ML.
  Zebrafish BarH-like genes define discrete neural domains in the early embryo.
  Gene Expr Patterns. 2006 6:347-52.
• Li J, Mack JA, Souren M, Yaksi E, Higashijima S, Mione M, Fetcho JR, Friedrich RW.
  Early development of functional spatial maps in the zebrafish olfactory bulb.
  J Neurosci. 2005 25:5784-95.
• Costagli A, Kapsimali M, Wilson SW, Mione M.
  Conserved and divergent patterns of Reelin expression in the zebrafish central nervous system.
  J Comp Neurol. 2002 450:73-93.
• Wendl T, Lun K, Mione M, Favor J, Brand M, Wilson SW, Rohr KB.
  Pax2.1 is required for the development of thyroid follicles in zebrafish.
  Development. 2002 15:3751-60.
• Barclay J, Balaguero N, Mione M, Ackerman SL, Letts VA, Brodbeck J, Canti C, Meir A, Page KM, Kusumi K, Perez-Reyes E, Lander ES, Frankel WN, Gardiner RM, Dolphin AC, Rees M.
  Ducky mouse phenotype of epilepsy and ataxia is associated with mutations in the Cacna2d2 gene and decreased calcium channel current in cerebellar Purkinje cells.
  J Neurosci. 2001 21:6095-104.
• Mione M, Shanmugalingam S, Kimelman D, Griffin K.
  Overlapping expression of zebrafish T-brain-1 and eomesodermin during forebrain development.
  Mech Dev. 2001 100:93-7.