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Genome integrity

Marco Foiani


Marco Foiani
c/o IFOM-IEO Campus
Via Adamello, 16 - 20139 Milan, Italy
Tel: +39 02 574303238 - Fax: +39 02 574303231

Marco Foiani is Full Professor of Molecular Biology at the Department of Biosciences, University of Milan.

Selected publications

  • Bermejo R, Capra T, Gonzalez-Huici V, Fachinetti D, Cocito A, Natoli G, Katou Y, Mori H, Kurokawa K, Shirahige K, Foiani M.
    Genome-organizing factors Top2 and Hmo1 prevent chromosome fragility at sites of S phase transcription.
    Cell. 2009 Sep 4;138(5):870-84.
  • Doksani Y, Bermejo R, Fiorani S, Haber JE, Foiani M.
    Replicon dynamics, dormant origin firing, and terminal fork integrity after double-strand break formation.
    Cell. 2009 Apr 17;137(2):247-58.
  • Branzei D, Vanoli F, Foiani M.
    SUMOylation regulates Rad18-mediated template switch.
    Nature. 2008 Dec 18;456(7224):915-20.
  • Bermejo R, Branzei D, Foiani M.
    Cohesion by topology: sister chromatids interlocked by DNA.
    Genes Dev. 2008 Sep 1;22(17):2297-301.
  • Branzei D, Foiani M.
    Regulation of DNA repair throughout the cell cycle.
    Nat Rev Mol Cell Biol. 2008 Apr;9(4):297-308.
  • Branzei D, Foiani M.
    Template switching: from replication fork repair to genome rearrangements.
    Cell. 2007 Dec 28;131(7):1228-30.
  • Branzei D, Foiani M.
    RecQ helicases queuing with Srs2 to disrupt Rad51 filaments and suppress recombination.
    Genes Dev. 2007 Dec 1;21(23):3019-26.
  • Bermejo R, Doksani Y, Capra T, Katou YM, Tanaka H, Shirahige K, Foiani M.
    Top1- and Top2-mediated topological transitions at replication forks ensure fork progression and stability and prevent DNA damage checkpoint activation.
    Genes Dev. 2007 Aug 1;21(15):1921-36.
  • Branzei D, Sollier J, Liberi G, Zhao X, Maeda D, Seki M, Enomoto T, Ohta K, Foiani M.
    Ubc9- and mms21-mediated sumoylation counteracts recombinogenic events at damaged replication forks.
    Cell. 2006 Nov 3;127(3):509-22.
  • Liberi G, Cotta-Ramusino C, Lopes M, Sogo J, Conti C, Bensimon A, Foiani M.
    Methods to study replication fork collapse in budding yeast.
    Methods Enzymol. 2006;409:442-62.
  • Lopes M, Foiani M, Sogo JM.
    Multiple mechanisms control chromosome integrity after replication fork uncoupling and restart at irreparable UV lesions.
    Mol Cell. 2006 Jan 6;21(1):15-27.
  • Branzei D, Foiani M.
    The DNA damage response during DNA replication.
    Curr Opin Cell Biol. 2005 Dec;17(6):568-75.
  • Pellicioli A, Foiani M.
    Signal transduction: how rad53 kinase is activated.
    Curr Biol. 2005 Sep 20;15(18):R769-71.
  • Chiolo I, Carotenuto W, Maffioletti G, Petrini JH, Foiani M, Liberi G.
    Srs2 and Sgs1 DNA helicases associate with Mre11 in different subcomplexes following checkpoint activation and CDK1-mediated Srs2 phosphorylation.
    Mol Cell Biol. 2005 Jul;25(13):5738-51.
  • Pellicioli A, Foiani M.
    Recombination at collapsed replication forks: the payoff for survival.
    Mol Cell. 2005 Jun 10;18(6):614-5.
  • Liberi G, Maffioletti G, Lucca C, Chiolo I, Baryshnikova A, Cotta-Ramusino C, Lopes M, Pellicioli A, Haber JE, Foiani M.
    Rad51-dependent DNA structures accumulate at damaged replication forks in sgs1 mutants defective in the yeast ortholog of BLM RecQ helicase.
    Genes Dev. 2005 Feb 1;19(3):339-50.
  • Cotta-Ramusino C, Fachinetti D, Lucca C, Doksani Y, Lopes M, Sogo J, Foiani M.
    Exo1 processes stalled replication forks and counteracts fork reversal in checkpoint-defective cells.
    Mol Cell. 2005 Jan 7;17(1):153-9.
  • Ira G, Pellicioli A, Balijja A, Wang X, Fiorani S, Carotenuto W, Liberi G, Bressan D, Wan L, Hollingsworth NM, Haber JE, Foiani M.
    DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1.
    Nature. 2004 Oct 21;431(7011):1011-7.
  • Liberi G, Foiani M.
    Initiation of DNA replication: a new hint from archaea.
    Cell. 2004 Jan 9;116(1):3-4.
  • Lopes M, Cotta-Ramusino C, Liberi G, Foiani M.
    Branch migrating sister chromatid junctions form at replication origins through Rad51/Rad52-independent mechanisms.
    Mol Cell. 2003 Dec;12(6):1499-510.
  • Lucca C, Vanoli F, Cotta-Ramusino C, Pellicioli A, Liberi G, Haber J, Foiani M.
    Checkpoint-mediated control of replisome-fork association and signalling in response to replication pausing.
    Oncogene. 2004 Feb 12;23(6):1206-13.
  • Ira G, Malkova A, Liberi G, Foiani M, Haber JE.
    Srs2 and Sgs1-Top3 suppress crossovers during double-strand break repair in yeast.
    Cell. 2003 Nov 14;115(4):401-11.
  • Foiani M.
    Molecular biology: Disruptive influence.
    Nature. 2003 May 15;423(6937):234-5.
  • Vaze MB, Pellicioli A, Lee SE, Ira G, Liberi G, Arbel-Eden A, Foiani M, Haber JE.
    Recovery from checkpoint-mediated arrest after repair of a double-strand break requires Srs2 helicase.
    Mol Cell. 2002 Aug;10(2):373-85.
  • Sogo JM, Lopes M, Foiani M.
    Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects.
    Science. 2002 Jul 26;297(5581):599-602.
  • Lopes M, Cotta-Ramusino C, Pellicioli A, Liberi G, Plevani P, Muzi-Falconi M, Newlon CS, Foiani M.
    The DNA replication checkpoint response stabilizes stalled replication forks.
    Nature. 2001 Aug 2;412(6846):557-61.
update: Oct 2009
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