Molecular and functional analysis of kinetochores

Selected publications

• Pagliuca C., Draviam V.M., Marco E., Sorger P.K., and De Wulf P.
  Roles for the conserved Spc105p/Kre28p complex in kinetochore-microtubule binding and the spindle assembly checkpoint.
  PLoS One, Oct 28;4(10):e7640 (2009)
• De Wulf P., Montani F., and Visintin R.
  Protein phosphatases take the mitotic stage.
  Current Opinion in Cell Biology, Sep 18. [Epub ahead of print]. (2009)
• Cohen R.L., Espelin C.W., De Wulf P., Sorger P.K., Harrison S.C., and Simons K.T.
  Structural and functional dissection of Mif2p, a conserved DNA-binding kinetochore protein.
  Molecualr Biology of the Cell, 19:4480-4491 (2008)
• Fukagawa T., and De Wulf P.
  Kinetochore composition, formation and organization. In: "The Kinetochore: from Molecular Discoveries to Cancer Therapy". Eds. De Wulf P., and Earnshaw W.C.
  Springer Publ., New York, pp. 133-191 (2008)
• De Wulf P., and Visintin R.
  Cdc14B and APC/C tackle DNA damage.
  Cell, 134: 210-212. (2008)
• Ciferri C., Pasqualato S., Screpanti E., Varetti G., Santaguida S., Dos Reis G., Maiolica A., Polka J., De Luca J.G., De Wulf P., Salek M., Rappsilber J., Moores C.A., Salmon E.D., and Musacchio A.
  Implications for kinetochore-microtubule attachment from the structure of an engineered Ndc80 complex.
  Cell, 133: 427-39. (2008).
• Miranda JJ.M., De Wulf P., Sorger P.K., and Harrison S.C.
  The yeast DASH complex decorates microtubules as a closed ring.
  Nature Structural and Molecular Biology, 12: 138-143. (2005)
• Liu X., and De Wulf P.
  Probing the ArcA-P signal transduction modulon of Escherichia coli by whole-genome transcriptional analysis and promoter-recognition profiling.
  Journal of Biological Chemistry, 279: 12588-12597. (2004).
• De Wulf P., McAinsh A.D., and Sorger P.K.
  Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes.
  Genes and Development, 17:2902-2921. (2003).